Information for Authors
American Journal of Cardiovascular Disease (AJCD, ISSN 2160-200X) is an open access online journal dedicated to
publication of original work in all areas of cardiovascular research. AJCD is primarily devoted to original research papers
(Main Research Articles and Brief Communications), and will also publish traditional Review articles and limited number of
important Case Reports. The goal of AJCD is to provide a forum for rapid dissemination of novel discoveries in basic and
clinical studies on all aspects of cardiovascular disease.
SUBMISSION OF MANUSCRIPT
General Policy
All manuscripts are submitted with the understanding that they have not been published elsewhere (except in the form of
an abstract or as part of a published lecture or thesis) and are not currently under consideration for publication by another
journal. It is the responsibility of the corresponding author to ensure that all authors have contributed to, read and approved
the final manuscript for submission. The authors should keep a copy of manuscript submitted in case of revision, rejection,
loss or damage. Receipt of manuscript will be acknowledged and a decision regarding acceptance made as soon as
possible. Accepted manuscripts may be subject to editorial revision without notice.
Peer Review Policy
All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic excellence.
Authors should provide 4 potential peer reviewers with detailed contact information including e-mail address. Authors may
also nominate 2 peers that they request are not sent the article for peer review for conflicts of interest or other appropriate
reasons – in such instances some reasonable justification must be given. These should be experts in their field of study,
who will be able to provide an objective assessment of the manuscript. If not provided, potential reviewers will be identified
by their publication record or recommended by the Editorial Board members.
Copyright Policy
By submitting a manuscript to AJCD, all authors agree that all copyrights of all materials included in the submitted
manuscript will be exclusively transferred to the publisher - e-Century Publishing Corporation once the manuscript is
accepted.
Once the paper is published, the copyright will be released by the publisher under the “Creative Commons Attribution
Noncommercial License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the published
article in any medium, provided that the original work is properly cited. If the manuscript contains a figure or table
reproduced from a book or another journal article, the authors should obtain permission from the copyright holder before
submitting the manuscript, and be fully responsible for any legal and/or financial consequences if such permissions are
not obtained.
All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-Century Publishing
Corporation (www.e-Century.org). Authors and readers are granted the right to freely use these files for all academic
purposes. By publishing paper in this journal, the authors grant the permanent right to the publisher to use any articles
published in this journal without any restriction including, but not limited to academic and/or commercial purposes. If you
are interested in using PDF, html, XML files or any art works published in this journal for any commercial purposes, please
contact the publisher at business@e-century.org.
Use of Human Subjects/Human Tissue and/or Animal Policy
Experiments involving human subjects should be done in accordance with the relevant ethical and legal standards
established and accepted by their host institution or in accordance with the Helsinki Declaration of 1975, or the Guidelines
of Office for Human Research Protections (OHRP) Human Subject Protections or equivalent. For studies that involved
human subjects, when informed consent has been obtained it should be indicated in the manuscript.
Experiments involving animals should follow the appropriate institution or the National Research Council Guide for the
care and use of laboratory animals.
Units and Abbreviations
System International (SI) units should be used for all measurements. All abbreviations should be explicitly defined at their
first occurrence except for those internationally acceptable. Abbreviations used in the genetic association reports will need
to follow the conventions detailed in the specific information requirements for genetic association reports. Any articles that
involve the description of enzymes will require the inclusion of the appropriate EC (Enzyme Commission) number as
recommended by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB).
Disclaimer
While the advice and information in the article are believed to be true and accurate on the date of its going to press, neither
the authors nor the editors can accept any legal responsibilities for any errors or omissions that may be made. The
publication makes no warranty, expressed or implied, with respect to the materials contained within.
PREPARATION OF MANUSCRIPT
All manuscripts should be written in standard grammatical English using computer software (Franklin Gothic Book normal
font, size 12, with single spacing between lines) and should be saved as single DOC (Word) file. Main Research Articles
and Brief Communications will follow a similar format as outlined below while Review Articles will follow a variation on this
(see below).
Main Research Articles are defined as being a substantial novel research study discussing the investigation of a clear
hypothesis or research question with appropriate methodologies (the use of more than one approach is encouraged) and
adequately powered studies and sample sizes. Noting the relevant sections (see below) there is no word limit on
manuscripts of this type except for the Abstract which should be a single unreferenced paragraph and no more than 350
words. There are no limits on the number of display items (tables and/or figures) although authors should try to be concise
and only include the most pertinent information. There are no supplementary tables or figures and every effort should be
made to include these in the main manuscript or alternatively reference should be made in the appropriate locations of the
manuscripts that such information will be available on request from the corresponding authors. There is no limit on the
number of references.
Brief Communications are a format that accommodates the reporting of high quality completed smaller scale studies yet
with important findings. This format is not for the reporting of preliminary or incomplete findings and the review process is
equally rigorous as that for Main Articles. The sections of a Brief Communication follow those of Main Articles (see below)
and there should not be additional sub-headings within these sections.
Review articles have a flexible format, are not of restricted length or reference number. Submissions of reviews must follow
that of Main Research Articles (see below) with the exception that appropriate headings be included for the main text of the
manuscript.
Layout requirements for submissions of Main Research Articles or Brief Communications:
1. cover letter
2. title page
3. abstract and keywords
4. main text
5. acknowledgements, if any
6. Declaration of conflicts of interest, if any
7. References
8. tables, if any
9. figure legends, if any
10. figures, if any
Cover Letter
The cover letter should include name, degree, address, telephone, fax and email of the corresponding author. A statement
that all authors have contributed to, read and approved the final manuscript for submission should be included if there are
multiple authors. Any editorial or financial conflict of interest (e.g., consultancy, stock ownership, equity interests, patent or
licensing agreements) should be clearly disclosed in the cover letter. The disclosure statement must be submitted upon
the acceptance. The cover letter should also be used to provide up the relevant details of 4 potential reviewers and 2 non-
reviewers for your manuscript giving appropriate explanations for the latter. Finally, if this submission is following the
solicitation or invitation of an Editorial Board member please state by whom.
Title Page
1. a concise title;
2. first name, middle initial, and last name of each author;
3. name of the department and institutional affiliation of each author.
4. the email address of each author.(*)
5. a running title.
(*) AJCD will only use the email address of the designated corresponding author in the final published manuscript but will
use all email addresses supplied to copy in all authors as additional email respondents to the correspondences we
routinely send to acknowledge receipt of manuscripts, and final decisions made on submitted manuscripts. AJCD would
also like, unless otherwise directed in the manuscript covering letter, to use these contact details to announce the contents
lists of future issues of AJCD and its sister journals! At no stage will AJCD sell such email lists to parties external to the e-
Century Publishing Corporation.
Abstract and Keywords
Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings and conclusions.
Include up to 10 key words or phrases at the end of the abstract.
Main Text
The main text should include Introduction, Materials and Methods, Results and Discussion. The Introduction should be
succinct, clearly stating the purpose and rationale of the study. In Materials and Methods, the procedures should be
described in sufficient detail to allow duplication by an independent observer. Results and Discussion should be divided.
They should be written concisely and logically with emphasis on novel findings and minimal repetition of text. For genetic
association reports refer to specific information requirements.
Acknowledgements
All acknowledgements (if any) should be included at the end of the main text before references and may include grant and
administrative support.
References (Please download EndNote X Style or Reference Manager Output Style for AJCD)
Reference published in AJCD should begin on a new page, be single-spaced and numbered in order of citation in the text,
including citations in tables and figure legends. Complete author citation is required (use of "et al" is not acceptable).
References should conform to the style of the Journal. Examples follow:
Journals: [1] Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to gastric cancer: focus
on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res 2009;1:44-54.
Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders. Edited by
Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048
Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of submission and
subsequent publication that the website address is relevant and functional.
In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place of volume and
page numbers.
Personal Communications: to be used very sparingly and in the context of no more than one sentence of associated text.
Submitted papers/unpublished data: Cite in text only.
Tables
All tables should be created with Microsoft Word Table Tool, single spacing between rows and cited consecutively in the
main text by Arabic numbers (Table 1, Table 2, etc). Include each table with a descriptive title on a separate page after the
references. Provide explanations for any nonstandard abbreviations in footnotes to the table.
All tables should be included in the Word File as the part of the complete manuscript after bibliography. Tables in image or
other formats are not acceptable. Authors are encouraged to split extremely large tables into multiple smaller ones to
facilitate publication and easiness to readers.
Figure Legends
Figure legends including figure number, a short title and detailed description should be embedded at the end of text file.
Figures
All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All figures must be
submitted in TIFF or JPEG format as separate files labeled with the corresponding numbers. Photographs of a person
should render them unidentifiable or include their written permission. Any figures involving Copyright issues should
conform to the Copyright policy.
Publication Fees
American Journal of Cardiovascular Disease is an open access journal which provides instant, worldwide and barrier-free
access to the full-text of all published articles. Publication charges allow the publisher to make the published material
available for free to all interested online readers.
The Publishing fee is $980 per article for our Editorial Board Members, $1280 per article for non-members. This will be
billed to the corresponding author. There is no extra charge for color figures. Authors who do not have appropriate funds
from developing countries can apply to have reduced fee by submitting a letter signed by the departmental chair to state
such a fact.
Manuscript Submission
The journal invites submission of all original research and review articles, editorials, letter to the editor and meeting
reports. AJCD will also consider methodological articles. All manuscripts should be submitted via email to:
editorial@AJCD.us and should be in compliance with the author’s guidelines described above. Please visit submission for
further information.
American Journal of Cardiovascular Disease (AJCD, ISSN 2160-200X) is an open access online journal dedicated to
publication of original work in all areas of cardiovascular research. AJCD is primarily devoted to original research papers
(Main Research Articles and Brief Communications), and will also publish traditional Review articles and limited number of
important Case Reports. The goal of AJCD is to provide a forum for rapid dissemination of novel discoveries in basic and
clinical studies on all aspects of cardiovascular disease.
SUBMISSION OF MANUSCRIPT
General Policy
All manuscripts are submitted with the understanding that they have not been published elsewhere (except in the form of
an abstract or as part of a published lecture or thesis) and are not currently under consideration for publication by another
journal. It is the responsibility of the corresponding author to ensure that all authors have contributed to, read and approved
the final manuscript for submission. The authors should keep a copy of manuscript submitted in case of revision, rejection,
loss or damage. Receipt of manuscript will be acknowledged and a decision regarding acceptance made as soon as
possible. Accepted manuscripts may be subject to editorial revision without notice.
Peer Review Policy
All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic excellence.
Authors should provide 4 potential peer reviewers with detailed contact information including e-mail address. Authors may
also nominate 2 peers that they request are not sent the article for peer review for conflicts of interest or other appropriate
reasons – in such instances some reasonable justification must be given. These should be experts in their field of study,
who will be able to provide an objective assessment of the manuscript. If not provided, potential reviewers will be identified
by their publication record or recommended by the Editorial Board members.
Copyright Policy
By submitting a manuscript to AJCD, all authors agree that all copyrights of all materials included in the submitted
manuscript will be exclusively transferred to the publisher - e-Century Publishing Corporation once the manuscript is
accepted.
Once the paper is published, the copyright will be released by the publisher under the “Creative Commons Attribution
Noncommercial License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the published
article in any medium, provided that the original work is properly cited. If the manuscript contains a figure or table
reproduced from a book or another journal article, the authors should obtain permission from the copyright holder before
submitting the manuscript, and be fully responsible for any legal and/or financial consequences if such permissions are
not obtained.
All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-Century Publishing
Corporation (www.e-Century.org). Authors and readers are granted the right to freely use these files for all academic
purposes. By publishing paper in this journal, the authors grant the permanent right to the publisher to use any articles
published in this journal without any restriction including, but not limited to academic and/or commercial purposes. If you
are interested in using PDF, html, XML files or any art works published in this journal for any commercial purposes, please
contact the publisher at business@e-century.org.
Use of Human Subjects/Human Tissue and/or Animal Policy
Experiments involving human subjects should be done in accordance with the relevant ethical and legal standards
established and accepted by their host institution or in accordance with the Helsinki Declaration of 1975, or the Guidelines
of Office for Human Research Protections (OHRP) Human Subject Protections or equivalent. For studies that involved
human subjects, when informed consent has been obtained it should be indicated in the manuscript.
Experiments involving animals should follow the appropriate institution or the National Research Council Guide for the
care and use of laboratory animals.
Units and Abbreviations
System International (SI) units should be used for all measurements. All abbreviations should be explicitly defined at their
first occurrence except for those internationally acceptable. Abbreviations used in the genetic association reports will need
to follow the conventions detailed in the specific information requirements for genetic association reports. Any articles that
involve the description of enzymes will require the inclusion of the appropriate EC (Enzyme Commission) number as
recommended by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB).
Disclaimer
While the advice and information in the article are believed to be true and accurate on the date of its going to press, neither
the authors nor the editors can accept any legal responsibilities for any errors or omissions that may be made. The
publication makes no warranty, expressed or implied, with respect to the materials contained within.
PREPARATION OF MANUSCRIPT
All manuscripts should be written in standard grammatical English using computer software (Franklin Gothic Book normal
font, size 12, with single spacing between lines) and should be saved as single DOC (Word) file. Main Research Articles
and Brief Communications will follow a similar format as outlined below while Review Articles will follow a variation on this
(see below).
Main Research Articles are defined as being a substantial novel research study discussing the investigation of a clear
hypothesis or research question with appropriate methodologies (the use of more than one approach is encouraged) and
adequately powered studies and sample sizes. Noting the relevant sections (see below) there is no word limit on
manuscripts of this type except for the Abstract which should be a single unreferenced paragraph and no more than 350
words. There are no limits on the number of display items (tables and/or figures) although authors should try to be concise
and only include the most pertinent information. There are no supplementary tables or figures and every effort should be
made to include these in the main manuscript or alternatively reference should be made in the appropriate locations of the
manuscripts that such information will be available on request from the corresponding authors. There is no limit on the
number of references.
Brief Communications are a format that accommodates the reporting of high quality completed smaller scale studies yet
with important findings. This format is not for the reporting of preliminary or incomplete findings and the review process is
equally rigorous as that for Main Articles. The sections of a Brief Communication follow those of Main Articles (see below)
and there should not be additional sub-headings within these sections.
Review articles have a flexible format, are not of restricted length or reference number. Submissions of reviews must follow
that of Main Research Articles (see below) with the exception that appropriate headings be included for the main text of the
manuscript.
Layout requirements for submissions of Main Research Articles or Brief Communications:
1. cover letter
2. title page
3. abstract and keywords
4. main text
5. acknowledgements, if any
6. Declaration of conflicts of interest, if any
7. References
8. tables, if any
9. figure legends, if any
10. figures, if any
Cover Letter
The cover letter should include name, degree, address, telephone, fax and email of the corresponding author. A statement
that all authors have contributed to, read and approved the final manuscript for submission should be included if there are
multiple authors. Any editorial or financial conflict of interest (e.g., consultancy, stock ownership, equity interests, patent or
licensing agreements) should be clearly disclosed in the cover letter. The disclosure statement must be submitted upon
the acceptance. The cover letter should also be used to provide up the relevant details of 4 potential reviewers and 2 non-
reviewers for your manuscript giving appropriate explanations for the latter. Finally, if this submission is following the
solicitation or invitation of an Editorial Board member please state by whom.
Title Page
1. a concise title;
2. first name, middle initial, and last name of each author;
3. name of the department and institutional affiliation of each author.
4. the email address of each author.(*)
5. a running title.
(*) AJCD will only use the email address of the designated corresponding author in the final published manuscript but will
use all email addresses supplied to copy in all authors as additional email respondents to the correspondences we
routinely send to acknowledge receipt of manuscripts, and final decisions made on submitted manuscripts. AJCD would
also like, unless otherwise directed in the manuscript covering letter, to use these contact details to announce the contents
lists of future issues of AJCD and its sister journals! At no stage will AJCD sell such email lists to parties external to the e-
Century Publishing Corporation.
Abstract and Keywords
Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings and conclusions.
Include up to 10 key words or phrases at the end of the abstract.
Main Text
The main text should include Introduction, Materials and Methods, Results and Discussion. The Introduction should be
succinct, clearly stating the purpose and rationale of the study. In Materials and Methods, the procedures should be
described in sufficient detail to allow duplication by an independent observer. Results and Discussion should be divided.
They should be written concisely and logically with emphasis on novel findings and minimal repetition of text. For genetic
association reports refer to specific information requirements.
Acknowledgements
All acknowledgements (if any) should be included at the end of the main text before references and may include grant and
administrative support.
References (Please download EndNote X Style or Reference Manager Output Style for AJCD)
Reference published in AJCD should begin on a new page, be single-spaced and numbered in order of citation in the text,
including citations in tables and figure legends. Complete author citation is required (use of "et al" is not acceptable).
References should conform to the style of the Journal. Examples follow:
Journals: [1] Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to gastric cancer: focus
on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res 2009;1:44-54.
Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders. Edited by
Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048
Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of submission and
subsequent publication that the website address is relevant and functional.
In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place of volume and
page numbers.
Personal Communications: to be used very sparingly and in the context of no more than one sentence of associated text.
Submitted papers/unpublished data: Cite in text only.
Tables
All tables should be created with Microsoft Word Table Tool, single spacing between rows and cited consecutively in the
main text by Arabic numbers (Table 1, Table 2, etc). Include each table with a descriptive title on a separate page after the
references. Provide explanations for any nonstandard abbreviations in footnotes to the table.
All tables should be included in the Word File as the part of the complete manuscript after bibliography. Tables in image or
other formats are not acceptable. Authors are encouraged to split extremely large tables into multiple smaller ones to
facilitate publication and easiness to readers.
Figure Legends
Figure legends including figure number, a short title and detailed description should be embedded at the end of text file.
Figures
All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All figures must be
submitted in TIFF or JPEG format as separate files labeled with the corresponding numbers. Photographs of a person
should render them unidentifiable or include their written permission. Any figures involving Copyright issues should
conform to the Copyright policy.
Publication Fees
American Journal of Cardiovascular Disease is an open access journal which provides instant, worldwide and barrier-free
access to the full-text of all published articles. Publication charges allow the publisher to make the published material
available for free to all interested online readers.
The Publishing fee is $980 per article for our Editorial Board Members, $1280 per article for non-members. This will be
billed to the corresponding author. There is no extra charge for color figures. Authors who do not have appropriate funds
from developing countries can apply to have reduced fee by submitting a letter signed by the departmental chair to state
such a fact.
Manuscript Submission
The journal invites submission of all original research and review articles, editorials, letter to the editor and meeting
reports. AJCD will also consider methodological articles. All manuscripts should be submitted via email to:
editorial@AJCD.us and should be in compliance with the author’s guidelines described above. Please visit submission for
further information.
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